15 Best Flea Drops For Dogs 2022 (Reviews and Buying Guide)


Dogs are the happiest and playful creatures. They love to roam around everywhere. Even though you take care of your pet, it might get affected by various insects when playing or walking outside the house. We have mentioned some of the best flea drops for your puppy.


  1. Bayer K9 Advantix II

Most people prefer this product. It kills ticks, fleas, and mosquitoes. The drops start working on your pup’s body after 10 minutes of applying. Apart from killing insects, it fights little bugs as well. Bayer K9 soothes your pet’s skin and plummets skin irritation and itching, and controls the spread of any disease.

The treatment stays for a month, and you need to put 2-3 drops on your dog’s back. Various doses and formulae are available, and you can select according to the pup’s size. It is suitable for 4lbs and above. Your pet can even play in the water after using the product as it is waterproof.

Some of the instructions you need to follow are to use it as directed.


-Kills through contact

-Destroys flea life stages

-Suitable for sizes

-Apply monthly

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2. Advecta II Flea Treatment

Advecta II Flea Treatment - Flea and Lice Prevention for Dogs, 4 Month Supply

This is the most affordable treatment. It starts working after 12 hours of applying and fights flea eggs, larvae, and adults. Besides, it controls chewing lice.

The dose is monthly and ideal for 3 lbs- 55 lbs. There is no odor, and it is waterproof. It is secure for dogs who are 7weeks or above.

It comes in a tube and is easy to use. Just apply it to your dog’s back. If your dog is huge, then apply it to 2-3areas.




-Lasts up to 30days

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3. TevraPet Activate II

TevraPet Activate II Flea and Tick Prevention for Dogs | Small 4-10 lbs | 4 Doses | Fast Acting Treatment and Control | Repels Mosquitoes

TevraPet Activate II is ideal for 4-10lbs and 7weeks or more. It has the same elements as Bayer K9 Advantix II. The ingredients in it kill the pests that come in contact. Thus, it is powerful as it does not cause skin irritation and stops the flea cycle.

The effect of the product stays up to 30 days, and you need not apply it even after bathing because it is waterproof. It is suitable for all sizes. So, if your pet grows up, you can continue to use TevraPet.


-Fight against fleas, mosquitoes, ticks, and other flies

-Destroys and prevent the flea life cycle

-Apply monthly


-Made in the USA

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4. Frontline Plus for Dogs

Frontline Plus Flea and Tick Treatment for Dogs (Large Dog, 45-88 Pounds, 6 Doses)

It is one of the best sellers. It is easy to use as it comes in a tube. Use is once, and the effect stays for around a month or more. The product starts to work after 12 hours. Frontline fights against flea development.

The flea drop is waterproof and is available in four different concentrations, suitable for 5lbs-132lbs. The treatment is only safe for 8weeks or more.

It has a limited satisfaction guarantee, as many have reviewed that the product does not work well, while others have given excellent reviews.


-Combat both ticks and fleas

-The treatment works for 30 days

-Ideal for 8weeks or above

-Works for 5-132lbs

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5. Natural Chemistry Flea and Tick Prevention

NAVTU Natural Chemistry 11261 Flea & Tick Squeeze On for Medium Dogs, 25-50 lb

The products contain synthetic chemicals. It combines mint, lemongrass, and cinnamon oils that kill and control different insects such as ticks, fleas, etc. Natural Chemistry works on dogs of all ages.

Buy once, and it will go for 5months. The medication is every month and offers three concentrations for all sizes of dogs.

The effectiveness might vary from place to place. According, to the reviews, people either like or dislike the fragrance. The product is not pricey, and hence, you can buy it.


-Contains three different oils

-Monthly dose

-Safe for all dogs

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Flea drops help prevent your dog from insects such as fleas, ticks, and mosquitoes. They can cause irritation and itchiness on the dog’s skin. If your dog loves to play outside and spends most of the time there, it is essential for flea drops.

There are various types of cure, such as sprays, powder, shampoo, dips, and oral medication, apart from drops. Each one of them has its significance. But people use drops because they are easy to use and more effective than others. Just one or two drops would remain for several weeks. You cannot wash it off after applying since the active chemicals go through your pet’s sweat glands.

Despite its effectiveness, drops have a limitation. If your dog mistakenly consumes it, it might be harmful to it. Thus, put the drop as per the instructions given. Until the drop gets dried, keep your dog far away from children and other pets. Even puppies are not safe for flea drop treatment. However, consult your veterinarian before you decide anything.


You need to look upon a few properties before buying the best flea drops for dogs.

Ingredients: Take a look at the ingredients and verify it by your vet because some of the chemicals might harm your pup. Also, not every element would be suitable for your small puppy.

– Age and Size: Not all the products are ideal for your dog. Various concentrations and formulae suit dogs of different ages and sizes.

Doses per box: The price of the products depends on the dosage. A flea drop can even cost twice the other product.

Duration of the treatment: Most treatments last up to a month or so. As a result, you need to worry about the daily dosage.

Natural or synthetic: Natural treatments are more preferred and are productive as well. They do not contain any chemicals and thus, do not harm your pet.

Other treatments: A few fleas drop also fights mosquitoes, mites, and chewing lice other than fleas and ticks. Therefore, if you have a lot of insects around you, then buy flea drops that kill other insects as well.


  1. PetAction Plus for Dogs
PetAction Plus for Dogs, 6 Doses Small Dogs 6-22 Lbs.

The drop is a monthly treatment for puppies that weigh between 6-22 lbs. Dogs who are eight weeks or older should use the product. It works on fleas, larvae, flea eggs, mites, ticks, mosquitoes, and chewing lice.


-For dogs who weigh between 6-22 lbs

-Monthly use

-The package comes with six-monthly doses

-Suitable for breeding, lactating, or pregnant dogs

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2. Vetri-Science Laboratories Flea and Tick Defense

VetriScience Laboratories (090050D.003) Flea + Tick Defense for 89 to 132-Pound Dogs and Puppies, 3 Doses

The product is pocket-friendly and is suitable for dogs that weigh 89-132 lbs. Dogs who are above eight weeks of age can safely use this product.


-Safe for dogs over eight weeks old

-Suitable for those who weigh 89-132 lbs

-Flights against ticks, fleas, and chewing lice

-Three-monthly doses pack


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3. Hartz Topical Flea and Tick Dual Action

Hartz UltraGuard Dual Action Topical Flea & Tick Treatment for Dogs and Puppies - 31-60lbs, 3 Monthly Treatments

The treatment acts fast if affected by fleas and ticks and prevents them for up to 30 days after applying the drop. It is suitable for all dog sizes and dogs over 12 weeks of age.


-Fight against pests and controls reinfestation

-Available in three-monthly dose

-Ideal for dogs above 12 weeks old

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4. Nutri-Vet Wellness K9 Defense

It is available in four concentrations and is ideal for dogs weighing 5-66 lbs. The drop not only saves against all stages of the flea life cycle but fights ticks, mosquitoes, fleas, mites, and lice for 30 days.


-Three-monthly doses available

-Four different concentrations are available

-Suitable for pets over 12 weeks old

-Effective against fleas, ticks, mites, lice, and mosquitoes

5. PETARMOR Plus for Dogs

  The drop starts working within 24 hours of applying. It is a 30-day treatment and fights fleas, chewing lice and, ticks. Also, it controls the formation of flea eggs and larvae for up to 12 weeks.


-Available in four different concentrations

-six-monthly doses available


6. Sentry Fiproguard Topical Flea and Tick

It is a waterproof formula that fights against ticks, chewing lice and, fleas for 30 days. The product is available in four various concentrations. The drop is ideal for 4-132 lbs dogs.


-Three monthly and six-monthly doses are available

-Safe for dogs eight weeks or above

-Available in 4 different concentrations

7. Virbac Effitix Flea/ Tick

The product starts working instantly on ticks, mosquitoes, and fleas. It is safe for dogs over eight weeks and is available in four concentrations.


-For 11-132 lbs

-pack available in 3 applications

8. Sentry Natural Defense Flea and Tick

The drop has five essential oils, and they are also active ingredients. It fights against fleas, ticks, and mosquitoes. The treatment works for four weeks.


-Available in four doses

-Three concentrations are available for different dog sizes

-Satisfying odor

-Kills and controls mosquitoes, ticks, and fleas

9. Terra Pet 100% Natural Flea and Tick

The drop contains 13 essential oils to fight ticks and fleas. Apply a small amount, lasting up to 2-5 days.


-The oil in the container lasts up to 4-6 months

-The pack has 1200 drops of oil

-Good odor

10. Direct Protect Plus Flea and Tick

Direct Protect is suitable for 5-132 lbs. The product effectively kills fleas, mosquitoes, chewing lice, and ticks.


-Waterproof after 12 hours of applying

-Pack of three-month dose

-Suitable for dogs above eight weeks or more

-Different concentrations are available

Flea drops are safe to use for adult dogs. But always consult your vet before buying any of the products. These were the best flea drops for dogs that would keep your pup away from insects.

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